Mukono Zonal Agricultural Research and Development Institute (MUZARDI) is one of the 16 Public Agricultural Research Institutes (PARIs) under the National Agricultural Research Organization (NARO) established under the National Agricultural Research System (NAR) Act of 2005.

Mukono ZARDI is mandated to carry out applied and adaptive agricultural research and technology dissemination in the Lake Victoria Crescent Agro-ecological Zone. It serves 22 Districts of Central Uganda which include; Mubende, Mityana, Luwero, Kyankwanzi, Mukono, Kayunga, Nakasongola, Nakaseke, Masaka, Kalangala, Buikwe, Kalungu, Lwengo, Mpigi, Kampala, Bukomansimbi, Gomba, Butambala, Buvuma, Wakiso, Kiboga and Kassanda. It is the most populous region with about 10 million people.

MUZARDI is located in Ntawo village within Mukono district, 20km East of Kampala and 2km off the Jinja-Kampala highway on 100 acres. It has a satellite station in Kamenyamiggo, Lwengo district on 320 acres.